Biocompatible cryogels are substances with a very high prospect for obtaining functional materials. The macroporous structure is of great importance for the use of cryogels as important materials in medicine, catalysis and some areas of biotechnology. In this review, the authors focused on methods for producing cryogels based on biopolymers, interpolyelectrolyte complexes of biopolymers and composite cryogels based on them. First, a brief theoretical information on the properties of cryogels and methods for producing cryogels based on biopolymers will be considered. The second part of the review contains the latest achievements in the production of cryogel based on biopolymer complexes and composite cryogels. The features of cryogenic synthesis and factors affecting the required final properties of cryogenic materials are considered. In the third part of the review, the fields of application of biocompatible cryogels in oil and gas fields of the type under consideration in biotechnology, catalysis and medicine are studied. In biotechnology, cryogenic materials are used to immobilize molecules and biological cells, as a basis for cell growth and as chromatographic materials for cell separation. In catalysis, cryogenic materials are used as a matrix for the immobilization of metal nanoparticles and enzymes. Biocompatible cryogels and composites based on them are widely used in medicine to restore bone and cartilage tissue, as well as for the proper transfer of drugs, ensuring the release of drugs in the body. The use of cryotropic polymer compositions with controlled hydrophobic properties as a reinforcing layer for creating hydro barrier screens in oil and gas fields is promising.

One of the promising and effective approaches of the modern control theory of complex technological systems in the conditions of uncertainty caused by the fuzziness of the initial information is an approach based on the use of expert evaluation methods and the theory of fuzzy sets.

This article presents a study of the properties of an automatic control system with the use of a pseudo-linear fuzzy PID controller built on the basis of a correction device with phase advance. 

One of the alternative methods of constructing control and regulation systems for objects that are indistinctly defined from the point of view of classical theory is the use of so-called fuzzy logic controllers.

Therefore, the development of fuzzy control controllers based on existing microcontrollers is a very urgent task, since a pseudo-linear fuzzy controller built on the basis of fuzzy sets and fuzzy logical I/O, under the condition of uncertainty of the disturbing effect, is able to provide higher quality indicators of the transient process than a traditional PID controller.

As pseudo-linear correction devices (PKU) we use: CU with amplitude suppression, with phase advance and with separate channels for amplitude and phase, since one of the main disadvantages of the PID controller is the presence of phase lag and high sensitivity to interference in the measuring channel.

The results of the project have a wide practical application in various industries, such as

medical institutions and healthcare facilities, large industrial enterprises, in the automotive industry, food, agricultural and livestock industries, as well as in industrial technology, the metallurgical industry; oil and gas industry.

In phase interferometric sensors (PID) based on arrays, the optical element itself acts as a sensitive element, which leads to a significant reduction in cost. The OB segment between two gratings is a Fabry-Perot interferometer. Under the influence of deformation and acoustic vibrations, the phase difference of signals from two adjacent Bragg gratings changes. Interferometric sensors are most sensitive to changes in the length of a fiber segment under the influence of external factors.

The principle of operation of distributed fiber-optic measuring complexes based on PID in the simplest case (in the case of one PID) is shown in Figure 3.6 and is as follows [4]. Each of the Bragg gratings RB1 and RB2 of the sensor reflects the pulse coming to it from the pulsed laser at the same Bragg wavelength.

 In this case, the time delay between the reflected pulses is equal to twice the propagation time of light in the sensitive element of the sensor – a fiber enclosed between the gratings.

The reflected pulses enter the compensating interferometer (CI), which, in turn, also bifurcates each of them. The delay introduced into the propagation of pulses by the arm 2 of the CI with respect to arm 1 ensures the overlap in time of the pulse reflected from the grating RB1 at the output of arm 2 and the pulse reflected from the grating RB2 at the output of arm 1 and their phase shift by ϕ 0 =π/2.

The problem of providing cheap electricity to both industrial enterprises and settlements has been and remains very relevant. More than 1 million people live in decentralized power supply zones. This is especially important for the remote areas of southern Kazakhstan, where there is no developed power transmission network, and the population receives electricity for 3-4 hours a day from a diesel-electric power station (DPP). The construction of small hydroelectric power plants (SHPPs) can change the living conditions of these people, ensure the energy security of the regions and contribute to the development of the economy.

At present, when solving problems related to the reconstruction and construction of new small hydropower plants, it is necessary to apply inexpensive and effective solutions for automation and remote control of power plants without the constant presence of maintenance personnel.

To effectively control and protect SHPs, a relatively large amount of functionality must be provided compared to larger power plants. A standardized intelligent electronic device (IED) can provide autonomous operation and prioritize safe water management. The IED shall be compact and integrated with the control of electrical and mechanical elements, including the water supply, communication, monitoring and protection system for small hydro power plants.

The article discusses the main elements of creating an ideal mathematical model of the operating procedure of the budget department for IT enterprises. The main technical problems arising in the context of deteriorating business conditions and economic instability are analyzed from the point of view of strategy. The introduction of information technology and the creation of specialized programs and modules are the primary methods for resolving the issues associated with the automation of business processes. By using such systems in various functional divisions, it is possible to reduce the amount of human factor and unneeded paperwork while also making the information gathered at the organization clear, accessible, and organized. Business process management modeling, which is a numerical optimization synthesis of the structure, components, and parameters of a business process, is incredibly important yet is still in its infancy. The cost of an IT project is the primary concern of the developed principles of mathematical modeling of business process management. The baseline data for the generated model, as well as its structure and the findings obtained, can alter dramatically throughout the simulation depending on the nature and peculiarities of each specific project. The research under discussion is aimed at increasing competitiveness in the market and maximizing the overall strategy of the organization. When constructing a mathematical model, the author pays special attention to the methods of mathematical modeling of a business process based on the principles of queuing theory. The created model will allow budget departments of IT companies to evaluate and improve their activities.

The article presents an overview of the application of technologies and methods of microcapsules in modern pharmaceuticals and the food industry. One of the most important tasks of healthcare is to provide the population with safe, effective, high-quality and affordable medicines. The analysis of the main rates of development of domestic medicines in the pharmaceutical market of Kazakhstan remains relevant. Microcapsulation is analyzed for physical, chemical, physico-chemical forms. With the help of microcapsulation, the following tasks can be solved: to reduce the reactivity of medicines, extend the shelf life of unstable and perishable medicines, reduce the toxicity of the substance, give the substance new physical properties, reduce volatility, change density, hide color, taste, smell. Microcapsules make it possible to ensure the long-term effect of medicines. Microcapsulation achieves: protection of unstable drugs from environmental influences (vitamins, antibiotics, enzymes, vaccines, serums, etc.); hiding the taste of bitter medicines; isolation of medicines in the desired part of the gastrointestinal tract (intestinalsoluble microcapsules); the question of obtaining high-quality capsules with properties and characteristics that dissolve in the desired environment, retain the therapeutic effect and at the same time meet the requirements of the consumer (ease of use, efficiency, reasonable cost) is still open.

This article focuses on improving the human and machine interface, which should ensure efficient processing of data and knowledge in simple, fast and accessible ways. One of the ways to organize it is the introduction of the manuscript (entering text, drawings, drawings, etc.). Handwritten signatures can be considered as handwritten words, but they are more suitable for drawings, because the signer tries to make his signature unique, using not only his first and last names, but also additional graphic elements. Creating a signature is quite simple, although it is impossible to reproduce the recording speed.

The signature has long been used to certify the authenticity of documents and verify (authenticate) an individual. In principle, the signature examination is used during the forensic examination. Signature recognition can be carried out by sequential verification of the signature to each known person. The signature recognition methodology includes a verification methodology and processing of verification results. One of the modern areas of interface improvement is the development and research of software for signature recognition and visualization.

The advent of modern computer input tools has led to the emergence of a new type of online signature describing the signature creation process, not the result. Moreover, not only the coordinates of points on the line, but also a sequence of vectors of parameter values for each of the values of pressure, direction and speed of movement, the angle of adaptation of the pen and the signature time.

This article is devoted to the problem of a high level of oncological diseases of the population of the Republic of Kazakhstan. The analysis of the presented statistical data indicates an annual increase in the number of detection of registered oncological diseases in the population of the Republic of Kazakhstan. With regard to our region, the annual increase in the number of cancer detection in the population of the Abai region, which is undoubtedly due to the existence of the former Semipalatinsk nuclear test site on this territory, leads to the need for further research to improve the prediction of the treatment process of patients with cancer.

Currently, the method of radioiodotherapy presented in the work is actively used for the treatment of oncological diseases, and in particular thyroid cancer. This method of treatment allows you to destroy cancer cells, surgical removal of which is not possible. An accurate calculation of the activity of the drug to be taken by the patient allows you to reduce the dose load on the patient and at the same time achieve the desired therapeutic effect. The paper presents formulas that are used to calculate the radiation dose of patients for the successful treatment of thyroid cancer. This method of treatment is carried out in the department of "Radionuclide Therapy" of the Center for Nuclear Medicine and Oncology of Semey.