Encapsulation of biologically active additives and probiotics by spraying

This article discusses the encapsulation of biologically active additives (BAA) and probiotics by spraying method. Today, a large number of BAA are registered in the country, the issue of rational classification of BAA is relevant. In the production of BAA, the use of plants, fungi and BAA that pose a danger to human life and health is not allowed. Currently, the importance of probiotics for enhancing and maintaining human immunity is emphasized.

There are many technologies for encapsulating dietary supplements and probiotics: extrusion, spray drying, spray freezing, addition to the matrix, gel encapsulation, encapsulation in a fluidized bed. Based on the literature review, alginate polymer encapsulation technologies are considered.

Sodium alginate was selected as the materials for the experiments. A solution of sodium alginate has been prepared. Capsules obtained from 0.5% sodium alginate are soft, with an inhomogeneous surface, not spherical in shape, which is due to the low viscosity of sodium alginate, the average size was 2,0×10^-3м.

In an experiment with a concentration of a solution of 1% sodium alginate, it was not possible to obtain capsules by spraying due to the high viscosity. The capsules were obtained by the drip method, had a rounded shape, dense structure, the average size was 3,2×10^-3м.

1. Tendencii razvitija rynka BAD v Respublike Kazahstan. https://pharm.reviews/analitika/item/29-tendentsii-razvitiya-rynkabad-v-respublike-kazakhstan-2013-2014-god [29.05.2023]. (In Russian).

2. O bezopasnosti pishhevoj produkcii. Ponjatie «pishhevaja produkcija»: Tehnicheskij reglament Tamozhennogo sojuza 021/2011 ot 09.12.2011 // Pravovoj portal Evrazijskogo jekonomicheskogo sojuza.URL:http://www.eurasiancommission.org/ru/act/texnreg/deptexreg/tr/Documents/TR%20TS%20PishevayaProd.pdf. [28.05.2023]. (In Russian).

3. Zhumadilova G.A. (2020) Issledovanie processa inkapsulirovanija probiotikovs cel'ju sozdanija oborudovanija [Investigation of the process of encapsulation of probiotics in order to create equipment]. diss. ...РhD – 6D072400. – Semey: Shakarim State University of Semey, – p.131. (In Russian).

4. Kakimov A.K., Kakimova Zh.H., Zharykbasova K.S., Bepeeva A.E., Mirasheva G.O., Dzhumazhanova M.M., Zhumadilova G.A. (2017) Inkapsulirovanie biologicheski aktivnyh dobavok i ih ispol'zovanie pri proizvodstve pishhevyh produktov [Encapsulation of biologically active additives and their use in food production]: monograph. – RSE on PCV Shakarim State University of Semey. – Almaty, – 218 s. (In Russian).

5. Burgain J., Gaiani C., Linder M., Scher J. Encapsulation of probiotic living cells: From laboratory scale to industrial applications. Journal of Food Engineering 104, 2011. – Р.467-483. (In English).

6. Rowley J.A., Madlambayan G., Mooney D.J. Alginate hydrogels as synthetic extracellular matrix materials. Biomaterials 20 (1), 1999. – Р. 45-53. (In English).

7. Krasaekoopt W., Bhandari B., Deeth H. Evaluation of encapsulation techniques of probiotics for yoghurt. International Dairy Journal 13 (1), 2003. – Р. 3-13. (In English).

8. Cook M.T., Tzortzis G., Charalampopoulos D.,. Khutoryanskiy V. V. Microencapsulation of probiotics for gastrointestinal delivery. Review//Journal of Controlled Release, – 2012. – Р. 56-67. (In English).

9. Muratbayev A.M. (2021) Kapsulalanғan biologijalyқ belsendі қospalardy қoldanyp өndіrіlgen,tamaқ өnіmderіnің қauіpsіzdіgіn қamtamasyz etudің tәzhіribelіk aspektіlerі [Practical aspects of ensuring the safety of food products produced using encapsulated biologically active additives]. diss. ... РhD – 6D073500. – Semey: Shakarim University of Semey, – 169 P. (In Russian).

10. https://farmf.ru/prochee/mikrokapsulirovanie-texnologiya-i-vspomogatelnye-veshhestva/ Микрокапсулирование. Технология и вспомогательные вещества [20.05.2023]. (In Russian).

11. https://www.diapazon-pharm.ru/raspylitelnaya-sushka-metody-i-tehnologiya Распылительная сушка: методы и технология [20.05.2023]. (In Russian).

12. https://farmf.ru/prochee/kapsuly-ix-vidy-vspomogatelnye-veshhestva-texnologii-napolneniya/ Капсулы, их виды, вспомогательные вещества, технологии наполнения [20.05.2023]. (In Russian).

13. Morgan R, Blagdon P (1993) Methods of encapsulating liquids in fatty matrices and products thereof, US patent 5204029. (In English).

14. Gavory C, Abderrahmen R, Bordes C, Chaussy D, Belgacem MN, et al. (2014) Encapsulation of a pressure sensitive adhesive by spray-cooling: Optimum formulation and processing conditions. Adv Powder Technol 292-300. (In English).

15. Okuro PK, Junior FM, Favaro-Trindade CS (2013) Technological Challenges for Spray Chilling Encapsulation of Functional Food Ingredients. Food Technol Biotechnol 51: 171-82. (In English).