kaz44Вестник Университета Шакарима. Серия технические наукиBulletin of Shakarim University. Technical Sciences2788-79953006-0524«Шәкәрім университеті» КеАҚ10.53360/2788-7995-2026-1(21)-78kaz44-2353Research ArticleХИМИЧЕСКАЯ ТЕХНОЛОГИЯ (ОРИГИНАЛЬНАЯ СТАТЬЯ)CHEMICAL TECHNOLOGY (ORIGINAL ARTICLE)БЕНТОНИТ И ГУМИНОВЫЕ ВЕЩЕСТВА: СОСТАВ, СВОЙСТВА И МЕДИЦИНСКОЕ ПРИМЕНЕНИЕBENTONITE AND HUMIC SUBSTANCES: COMPOSITION, PROPERTIES, AND MEDICAL APPLICATIONShttps://orcid.org/0009-0009-1709-0130ЖабаеваН. Е.ZhabayevaN. E.

Нурай Еркиновна Жабаева – магистрант кафедры «Химии и технологии органических веществ, природных соединений и полимеров» 

050040, г. Алматы, проспект аль-Фараби, 71

Nuray Zhabayeva – master's student of the department «Chemistry and technology of organic substances, natural compounds and polymers» 

050040, Almaty, 71 Al-Farabi Avenue

nurai_zhabaeva@mail.ruhttps://orcid.org/0000-0002-4110-678XЖумагалиеваШ. Н.ZhumagalievaSh. N.

Шынар Нурлановна Жумагалиева – доктор химических наук, профессор кафедры «Химии и технологии органических веществ, природных соединений и полимеров» 

050040, г. Алматы, проспект аль-Фараби, 71

Shynar Zhumagalieva – doctor of chemical sciences, professor of the department «Chemistry and technology of organic substances, natural compounds and polymers» 

050040, Almaty, 71 Al-Farabi Avenue

shynarnur@mail.ruhttps://orcid.org/0000-0002-2665-2539АбиловЖ. А.AbilovZh. A.

Жарылкасын Абдуахитович Абилов – доктор химических наук, профессор кафедры «Химии и технологии органических веществ, природных соединений и полимеров» 

050040, г. Алматы, проспект аль-Фараби, 71

Jarylkasyn Abilov – doctor of chemical sciences, professor of the department «Chemistry and technology of organic substances, natural compounds and polymers» 

050040, Almaty, 71 Al-Farabi Avenue

abilovs51@mail.ruhttps://orcid.org/0009-0006-8763-5632ГазизовА. Д.GazizovA. D.

Айдын Долдашевич Газизов – заведующий научно-исследовательской лабораторией 

050060, г. Алматы, проспект аль-Фараби, 75В

Aidyn Gazizov – head of the scientific research laboratory of the Research Centre of Ecology and Environment of Central Asia 

050060, Almaty, 75V Al-Farabi Avenue

gaziz.aydin@gmail.comКазахский национальный университет имени аль-ФарабиКазахстанAl-Farabi Kazakh National UniversityKazakhstanНаучно-исследовательский центр экологии и окружающей средыКазахстанResearch Centre of Ecology and Environment of Central AsiaKazakhstan20262505202611(21)723740Copyright © Жабаева Н.Е., Жумагалиева Ш.Н., Абилов Ж.А., Газизов А.Д., 20262026Жабаева Н.Е., Жумагалиева Ш.Н., Абилов Ж.А., Газизов А.Д.Zhabayeva N.E., Zhumagalieva S.N., Abilov Z.A., Gazizov A.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://tech.vestnik.shakarim.kz/jour/article/view/2353

В статье представлен систематический обзор состава, физико-химических свойств и биологической активности бентонитовых глин, включая бентониты Таганского месторождения, а также гуминовых веществ и их применения в медицине. Актуальность работы обусловлена уникальными адсорбционными и регенеративными свойствами этих природных материалов, что определяет их перспективность в детоксикации и терапии различных патологий. Проанализированы литературные данные о минералогическом составе бентонита (преимущественно монтмориллонита), его набухающих и сорбционных характеристиках, а также о химическом составе гуминовых и фульвокислот. Рассмотрены основные направления медицинского применения: бентонитовые энтеросорбенты для коррекции острых и хронических интоксикаций и диарей, наружные лекарственные формы (гели и мази) для заживления ожогов и ран, а также нутрицевтическое и иммуномодулирующее применение гуминовых веществ. Анализ экспериментальных и клинических данных свидетельствует о синергетическом эффекте совместного использования бентонита и гуминовых комплексов, проявляющемся в повышенной сорбционной способности, пролонгированном действии и снижении токсичности. Полученные данные демонстрируют научную значимость изучения взаимодействия этих природных компонентов и их фармакологического потенциала. Практическая ценность работы заключается в обосновании перспектив разработки природных энтеросорбентов и биологически активных добавок детоксикационного действия.

The article presents a systematic review of the composition, physicochemical properties, and biological activity of bentonite clays, including bentonites from the Tagan deposit, as well as humic substances and their applications in medicine. The relevance of the work is determined by the unique adsorption and regenerative properties of these natural materials, which define their prospects for use in detoxification and therapy of various pathological conditions. Literature data on the mineralogical composition of bentonite (predominantly montmorillonite), its swelling and sorption characteristics, as well as the chemical composition of humic and fulvic acids were analyzed. The main directions of medical application are considered, including bentonite enterosorbents for the correction of acute and chronic intoxications and diarrhea, topical dosage forms (gels and ointments) for healing burns and wounds, as well as the nutraceutical and immunomodulatory use of humic substances. Analysis of experimental and clinical data indicates a synergistic effect of the combined use of bentonite and humic complexes, manifested in increased sorption capacity, prolonged action, and reduced toxicity. The obtained data demonstrate the scientific significance of studying the interaction of these natural components and their pharmacological potential. The practical value of the work lies in substantiating the prospects for the development of natural enterosorbents and biologically active additives with detoxifying effects.

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The authors declare that there are no conflicts of interest present.